{"id":357,"date":"2017-05-01T21:59:09","date_gmt":"2017-05-01T21:59:09","guid":{"rendered":"http:\/\/iduron.zool.design\/?post_type=avada_portfolio&#038;p=357"},"modified":"2020-01-23T14:40:14","modified_gmt":"2020-01-23T14:40:14","slug":"heparin-red","status":"publish","type":"avada_portfolio","link":"https:\/\/heparinanalysisproducts.com\/our-products\/heparin-red\/","title":{"rendered":"HEPARIN RED"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-parallax-none nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-image: url(&quot;https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/2017\/05\/bgrd-heparin-quantification-2.jpg&quot;);background-position: center center;background-repeat: no-repeat;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#f7f7f7;border-style:solid;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_5 1_5 fusion-one-fifth fusion-column-first fusion-no-small-visibility\" style=\"width:20%;width:calc(20% - ( ( 4% + 4% ) * 0.2 ) );margin-right: 4%;margin-top:15px;margin-bottom:15px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_3_5 3_5 fusion-three-fifth product-text-section fusion-animated\" style=\"width:60%;width:calc(60% - ( ( 4% + 4% ) * 0.6 ) );margin-right: 4%;margin-top:15px;margin-bottom:15px;\" data-animationType=\"fadeInDown\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\" id=\"product-text-section-01\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-one page-heading\" style=\"margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h1 class=\"title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:90;line-height:1;\">HEPARIN RED<\/h1><\/div><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two product-text-section\" style=\"margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h2 class=\"title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:63;line-height:1;\">APPLICATION<\/h2><\/div><div class=\"fusion-text fusion-text-1\"><p style=\"text-align: center;\">Heparin Red<sup>\u00ae<\/sup> is a synthetic fluorescent probe that changes intensity when interacting with heparin. Supplied by our partners Redprobes in Germany the Heparin Red<sup>\u00ae<\/sup> technology is available as two kits:<br \/>\n1. The Heparin Red<sup>\u00ae<\/sup> Kit for quantification of heparin in human plasma<br \/>\n2. Heparin Red<sup>\u00ae<\/sup> Ultra for quantification of heparin in crude heparin extraction.<\/p>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:15px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\" style=\"margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h2 class=\"title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:63;line-height:1;\">DESCRIPTION<\/h2><\/div><div class=\"fusion-text fusion-text-2\"><p style=\"text-align: center;\">The Heparin Red<sup>\u00ae<\/sup> Kit measures \u201cchemical\u201d heparin in blood plasma at concentrations in \u00b5g\/mL, not the effect of heparin on the clotting cascade <sup>[1]<\/sup>.<\/p>\n<p style=\"text-align: center;\">Additionally, the Kit is developing into a tool for pharmacokinetic studies of non-anticoagulant heparins <sup>[2]<\/sup>, a class of chemicals with enormous promise for future drug therapies.<\/p>\n<p style=\"text-align: center;\"><strong>CONVENIENT<\/strong> &#8211; mix-and-read fluorescence assay for microplates<br \/>\n<strong>SENSITIVE<\/strong> &#8211; quantification down to low \u00b5g\/mL with detection of heparins in only 20 \u00b5L plasma<br \/>\n<strong>VERSATILE <\/strong>&#8211; detection of non-anticoagulant heparins and other sulphated polysaccharides<br \/>\n<strong>QUALITY<\/strong> &#8211; robust, protein-free reagents<\/p>\n<p style=\"text-align: center; font-size: 12px;\"><strong>[1]<\/strong> Warttinger U, Giese C, Harenberg J, Holmer E, Kr\u00e4mer R.\u00a0<strong>A fluorescent probe assay (Heparin Red) for direct detection of heparins in human plasma. <\/strong>Anal. Bioanal. Chem. 2016, 408, 8241-8251.<\/p>\n<p style=\"text-align: center; font-size: 12px;\"><strong>[2]<\/strong> Galli M, Magen H, Einsele H, Chatterjee M, Grasso M, Specchia G, Barbieri P, Paoletti D, Pace S, Sanderson R, D, Rambaldi A, Nagle A.\u00a0<strong>Roneparstat (SST0001), an innovative heparanase (HPSE) inhibitor for multiple myeloma (MM) therapy: first in man study.<\/strong>\u00a0Blood 2015, 126, 3246-3246.<\/p>\n<p style=\"text-align: center;\"><strong>Heparin Red<sup>\u00ae<\/sup> Ultra<\/strong><\/p>\n<p style=\"text-align: center;\">Heparin Red<sup>\u00ae<\/sup> Ultra is a simple and easy to use assay for measuring chemical heparin in complex matrices<\/p>\n<p style=\"text-align: center;\">The 2008 heparin adulteration crisis highlighted the need for a rapid, reliable method for screening raw heparin extractions \u2013 the Heparin Red<sup>\u00ae<\/sup> Ultra kit meets this need. The kit is ideal for testing heparin concentrations in crude animal extracts, and so will be of significant value to the heparin manufacturing industry <sup>[1]<\/sup>.<\/p>\n<p style=\"text-align: center;\">The assay measures \u201cchemical\u201d heparin concentrations in \u00b5g\/mL, not the effect of heparin on the clotting cascade. Heparin Red<sup>\u00ae<\/sup> Ultra was reported to suppress interference by nucleic acids and detect heparin in urine <sup>[1]<\/sup>.<\/p>\n<p style=\"text-align: center;\">In the publication, we only speculate about the application for crude animal extracts but have not used such samples, we have used \u201cmodel solutions\u201d that contain heparin spikes instead.<\/p>\n<p style=\"text-align: center;\"><strong>CONVENIENT<\/strong> &#8211; mix-and-read fluorescence assay for microplates<br \/>\n<strong>SENSITIVE<\/strong> \u2013 small sample volumes with quantification in the low \u00b5g\/mL range<br \/>\n<strong>QUALITY<\/strong> &#8211; robust, protein-free consistent reagents<\/p>\n<p style=\"text-align: center; font-size: 12px;\"><strong>[1]<\/strong>\u00a0Warttinger U, Kr\u00e4mer R.\u00a0<strong>Quantification of heparin in complex matrices (including urine) using a mix-and-read fluorescence assay.<\/strong>arXiv:1611.02482<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_5 1_5 fusion-one-fifth fusion-column-last fusion-no-small-visibility\" style=\"width:20%;width:calc(20% - ( ( 4% + 4% ) * 0.2 ) );margin-top:15px;margin-bottom:15px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #a8c6e9;background-position: center center;background-repeat: no-repeat;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;border-width: 0px 0px 0px 0px;border-color:#f7f7f7;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_5 1_5 fusion-one-fifth fusion-column-first\" style=\"width:20%;width:calc(20% - ( ( 4% + 4% ) * 0.2 ) );margin-right: 4%;margin-top:15px;margin-bottom:15px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_3_5 3_5 fusion-three-fifth\" style=\"width:60%;width:calc(60% - ( ( 4% + 4% ) * 0.6 ) );margin-right: 4%;margin-top:15px;margin-bottom:15px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\" style=\"margin-top:60px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h2 class=\"title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:63;line-height:1;\">SHIPPING AND STORAGE<\/h2><\/div><div class=\"fusion-text fusion-text-3\"><p style=\"text-align: center;\">Both kits are shipped refrigerated and are available worldwide.<\/p>\n<p style=\"text-align: center;\">The kits are shipped on refrigerated on cold packs and stored at 4\u02daC.<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_5 1_5 fusion-one-fifth fusion-column-last\" style=\"width:20%;width:calc(20% - ( ( 4% + 4% ) * 0.2 ) );margin-top:15px;margin-bottom:15px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #faf7ea;background-position: center center;background-repeat: no-repeat;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;border-width: 0px 0px 0px 0px;border-color:#f7f7f7;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:0px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-section-separator section-separator bigtriangle fusion-section-separator-1\"><div class=\"fusion-section-separator-svg\" style=\"padding:0;margin-left: 0px;margin-right: 0px;\"><svg class=\"fusion-big-triangle-candy\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" version=\"1.1\" width=\"100%\" height=\"100\" viewBox=\"0 0 100 100\" preserveAspectRatio=\"none\" style=\"fill:#a8c6e9;padding:0;\"><path d=\"M-1 -1 L50 99 L101 -1 Z\"><\/path><\/svg><\/div><div class=\"fusion-section-separator-spacer\"><div class=\"fusion-section-separator-spacer-height\" style=\"height:99px;\"><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:15px;margin-bottom:15px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"woocommerce columns-2 \"><ul class=\"products clearfix products-2\">\n<li class=\"product type-product post-1468 status-publish first instock product_cat-heparin-red shipping-taxable product-type-simple product-grid-view\">\n\t<div class=\"fusion-product-wrapper\">\n<a href=\"https:\/\/heparinanalysisproducts.com\/product\/heparin-red-kit\/\" class=\"product-images\" aria-label=\"Heparin Red\u00ae Kit\">\n\n<div class=\"featured-image\">\n\t\t<img width=\"500\" height=\"500\" src=\"https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder.png\" class=\"woocommerce-placeholder wp-post-image\" alt=\"Placeholder\" srcset=\"https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-66x66.png 66w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-150x150.png 150w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-200x200.png 200w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-300x300.png 300w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-400x400.png 400w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-600x600.png 600w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-768x768.png 768w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-800x800.png 800w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-1024x1024.png 1024w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder.png 1200w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\n\t\t\t\t\t\t<div class=\"cart-loading\"><i class=\"awb-icon-spinner\" aria-hidden=\"true\"><\/i><\/div>\n\t\t\t<\/div>\n<\/a>\n<div class=\"fusion-product-content\">\n\t<div class=\"product-details\">\n\t\t<div class=\"product-details-container\">\n<h3 class=\"product-title\">\n\t<a href=\"https:\/\/heparinanalysisproducts.com\/product\/heparin-red-kit\/\">\n\t\tHeparin Red\u00ae Kit\t<\/a>\n<\/h3>\n<div class=\"fusion-price-rating\">\n<div class=\"cat-number\"><b>Catalogue #<\/b> HR001<\/div><div class=\"qty-number\"><b>Quantities available<\/b> 1 Kit<\/div>\n<div class=\"post-content woocommerce-product-details__short-description\">\n\t<p>For the direct detection of heparins in human plasma.<\/p>\n<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\t<div class=\"product-buttons\">\n\t\t<div class=\"fusion-content-sep sep-none\"><\/div>\n\t\t<div class=\"product-buttons-container clearfix\">\n<br><div class=\"fusion-button-wrapper\"><style>.fusion-button.button-1{border-radius:2px 2px 2px 2px;}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-default button-1 fusion-button-default-span fusion-button-default-type product_contact_button\" target=\"_self\" href=\"\/get-in-touch\/\"><span class=\"fusion-button-text\">Ask us for a price<\/span><\/a><\/div>\n<a href=\"https:\/\/heparinanalysisproducts.com\/product\/heparin-red-kit\/\" class=\"show_details_button\" style=\"float:none;max-width:none;text-align:center;\">\n\tDetails<\/a>\n\n\n\t<\/div>\n\t<\/div>\n\n\t<\/div> <\/div>\n<\/li>\n<li class=\"product type-product post-1470 status-publish last instock product_cat-heparin-red shipping-taxable product-type-simple product-grid-view\">\n\t<div class=\"fusion-product-wrapper\">\n<a href=\"https:\/\/heparinanalysisproducts.com\/product\/heparin-red-ultra\/\" class=\"product-images\" aria-label=\"Heparin Red\u00ae Ultra\">\n\n<div class=\"featured-image\">\n\t\t<img width=\"500\" height=\"500\" src=\"https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder.png\" class=\"woocommerce-placeholder wp-post-image\" alt=\"Placeholder\" srcset=\"https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-66x66.png 66w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-150x150.png 150w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-200x200.png 200w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-300x300.png 300w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-400x400.png 400w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-600x600.png 600w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-768x768.png 768w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-800x800.png 800w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder-1024x1024.png 1024w, https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/woocommerce-placeholder.png 1200w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\n\t\t\t\t\t\t<div class=\"cart-loading\"><i class=\"awb-icon-spinner\" aria-hidden=\"true\"><\/i><\/div>\n\t\t\t<\/div>\n<\/a>\n<div class=\"fusion-product-content\">\n\t<div class=\"product-details\">\n\t\t<div class=\"product-details-container\">\n<h3 class=\"product-title\">\n\t<a href=\"https:\/\/heparinanalysisproducts.com\/product\/heparin-red-ultra\/\">\n\t\tHeparin Red\u00ae Ultra\t<\/a>\n<\/h3>\n<div class=\"fusion-price-rating\">\n<div class=\"cat-number\"><b>Catalogue #<\/b> HRU001<\/div><div class=\"qty-number\"><b>Quantities available<\/b> 1 Vial<\/div>\n<div class=\"post-content woocommerce-product-details__short-description\">\n\t<p>For quality control of crude heparin.<\/p>\n<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\t<div class=\"product-buttons\">\n\t\t<div class=\"fusion-content-sep sep-none\"><\/div>\n\t\t<div class=\"product-buttons-container clearfix\">\n<br><div class=\"fusion-button-wrapper\"><style>.fusion-button.button-2{border-radius:2px 2px 2px 2px;}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-default button-2 fusion-button-default-span fusion-button-default-type product_contact_button\" target=\"_self\" href=\"\/get-in-touch\/\"><span class=\"fusion-button-text\">Ask us for a price<\/span><\/a><\/div>\n<a href=\"https:\/\/heparinanalysisproducts.com\/product\/heparin-red-ultra\/\" class=\"show_details_button\" style=\"float:none;max-width:none;text-align:center;\">\n\tDetails<\/a>\n\n\n\t<\/div>\n\t<\/div>\n\n\t<\/div> <\/div>\n<\/li>\n<\/ul>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-parallax-none nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-image: url(&quot;https:\/\/heparinanalysisproducts.com\/wp-content\/uploads\/2017\/05\/green_Strip.jpg&quot;);background-position: center center;background-repeat: no-repeat;padding-top:60px;padding-right:0px;padding-bottom:60px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 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class=\"title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:63;line-height:1;\">HOW TO ORDER OR REQUEST A QUOTE<\/h2><\/div><div class=\"fusion-text fusion-text-4\"><p style=\"text-align: center;\">Fill in the form <a href=\"https:\/\/heparinanalysisproducts.com\/get-in-touch\/\">here<\/a>, or email Iduron at <a href=\"mailto:info@iduron.co.uk\">info@iduron.co.uk<\/a>.<\/p>\n<p style=\"text-align: center;\">Please send a list of the products you would like along with your delivery address and we will reply with a quote and lead time.<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div>\n<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-5 worldwide-shipping nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: 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