Use for depolymerization of heparin, LMW heparin and heparan sulphate to component disaccharides.
USP monograph 207 – 1,6-Anhydro Derivative for Enoxaparin Sodium Ph. Eur. monograph 1097 – Enoxaparin sodium
High quality Enzymes purified from Flavobacterium heparinum (ATCC 13125) for depolymerization of heparin and LMW heparin including Enoxaparin Sodium.
Bacterial heparinases are eliminases that cleave the glycosidic linkage between amino sugars and uronic acids in heparin and when used in combination, heparinases bring about a near-complete depolymerisation of heparin to its constituent disaccharides.
At the site of cleavage these enzymes create a C4-C5 double bond in the uronic acid that absorbs at 232nm and can be used for the detection of degradation products.
Exceptionally pure and potent natural bacterial proteins; the specialist method of preparation gives baseline separation between the three heparinases producing very pure, world class enzymes.